Dextran catches increasing attentions as a drug carrier because of its biocompatibility,?biodegradability and ease of modification. In this study, we synthesized the derivated dextran by?grafting with 1-(3-aminopropyl) imidazole. The dextran-based nanoparticles with sizes of < 200 nm?were successfully prepared by nanoprecipitation, and its pH-sensitivities were investigated. The?samples were fully characterized by FTIR, 1H NMR, SEM, AFM and Zetasizer.
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作者
He Lei,Guo Liang Zhang
期刊
Advanced Materials Research
年份