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In order to improve the stability and decrease the cytotoxicity of silver nanoparticle (AgNP),a polyethyleneimine-modified reduced graphene oxide (PEI-rGO) was used as the substrate?of AgNPs, and a PEI-rGO–AgNP hybrid was prepared by anchoring the AgNPs on the reduced?graphene oxide surface. Such a hybrid showed substantially higher antibacterial activity?than polyvinyl pyrrolidone (PVP)-stabilized AgNP, and the AgNPs on PEI-rGO were more stable
than the AgNPs on PVP, resulting in long-term antibacterial effects. The hybrid showed?excellent water-solubility and lower cytotoxicity, suggesting the great potential application?as a sprayable graphene-based antibacterial solution.